Nanotherapeutics

Your Biopharmaceutical Development and Manufacturing Partner

Manufacturing

Nanotherapeutics has assembled a world-class team to apply new biomanufacturing technologies with existing manufacturing capabilities for biologic products that will provide the DoD and the US Government with the ability to rapidly respond to emerging disease threats and chemical, biologic, radiological and nuclear (CBRN) events.

Additionally, Nanotherapeutics is able to leverage its facility and capabilities to provide manufacturing and process development services to the biopharmaceutical industry.  Our primary manufacturing goal is to rapidly produce bulk drug substance according to the highest standards of quality. Along with its partners, Nanotherapeutics provides broad/flexible capabilities including:
 

  • Development laboratories and pilot plant for performing optimization of upstream, downstream and formulation functions
  • Biologics drug substance cGMP manufacturing space 
  • Analytical development
  • Oversight of small molecule synthesis and product release

Nanotherapeutics' manufacturing capabilities include proteins, antibodies, viral, bacterial and recombinant protein vaccines and gene therapy vectors and drug products. We have an integrated team of partners to support product/process development and manufacturing, from the stage of clinical development through the manufacturing of commercial supply. Our highly experienced team provides expertise from preclinical development through final product licensure in all relevant biologics production platforms.

NanoDRY®

One of the Company’s legacy manufacturing platforms is the NanoDRY® process. NanoDRY® is a rapid drying technique that produces particles on the nanometer to micrometer scale for efficient and reproducible delivery of large and small molecules. The NanoDRY® process uses a low-shear, low-temperature method of rapidly forming and growing nanoparticles to a desired size and shape in batch sizes from milligrams to hundreds of grams.  Using proprietary conditions, the NanoDRY® technique may be used to form microparticles of low molecular-weight compounds, peptides/proteins and DNA in combination with several excipients and polymers.  This scalable process, compared to milling, spray-drying, and Supercritical Fluid (SCF) Techniques, has been shown to improve powder flow, stability and dissolution/release profiles with close to 100% recovery of active compound.

Copyright 2017 NANOTHERAPEUTICS, INC.  All rights reserved.