Current Products

Medical Devices R&D Animal Studies 510(k) Market Partner Origen™ DBM         Orthofix

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In Progress

Origen™ DBM with Bioactive Glass is a bone void filler comprised of a gelatin carrier, Bioactive Glass (45s5) and human demineralized bone matrix (DBM) intended for transplantation. Origen™ has been formulated to reconstitute into a paste upon addition of a sterile fluid (e.g. sterile saline, water for injection). Origen™ is provided in a sterile, single-use syringe. Since Origen™ contains biological materials, some variations in product appearance and handling should be expected. Origen™ is pyrogen free.


Origen™ DBM with Bioactive Glass is indicated to be gently placed into bony voids or gaps of the skeletal system that are not intrinsic to the stability of the bony structure (e.g., the extremities and pelvis). These defects may be surgically created osseous defects or osseous defects created from traumatic injury to the bone. The product provides a bone graft substitute that remodels into the recipient's skeletal system.


Origen™ is the first off-the-shelf DBM-Bioactive Glass product available for use in an orthopedic clinical setting. As an adjuvant to demineralized bone matrix, Bioactive Glass facilitates operative site graft containment through rapid bone bonding and the subsequent activation of cellular osteogenesis. The combined properties of DBM and Bioactive Glass create a favorable environment for bone fusion. Origen™ is a novel composite allograft expressly designed to optimize surgical handling performance, graft stability, and osteoproductivity.

• Orthofix Orthopedic Reconstruction Products
  
• Orthofix Orthopedic Trauma Products